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Nature and Scope of Job:
We are seeking a Postdoctoral Researcher to conduct research in the field of synthetic biology by conducting research for containment of genetically engineered bacteria. You will work with a multi-disciplinary team of scientists and engineers who are passionate about achieving success while solving some of nation’s greatest challenges. This position is in the Systems and Synthetic Biology group in the Biosciences and Biotechnology Division.
• Conduct fundamental research for containment of genetically engineered bacteria by developing security mechanisms to constrain cell survival and function.
• Employ high throughput approaches to screen thousands of gene synthesis designs.
• Employ synthetic biology to implement biological circuits in environmentally relevant microorganisms and characterize efficacy in test beds of increasing complexity.
• Develop research plans, generate results, and publish peer-reviewed papers.
• Work with other scientists to write proposals and expand our program into new areas aligned with your expertise and interests.
• Write reports to funding agencies and participate in scientific conferences.
• Pursue independent (but complementary) research interests and interact with a broad spectrum of scientists internally and externally to the Laboratory.
• Publish research results in peer-reviewed scientific or technical journals and present results at external conferences, seminars, and/or technical meeting.
• Perform other duties as assigned.
• PhD in Biological Sciences, Bioengineering, or a relevant field with a strong emphasis in synthetic biology and microbiology.
• Experience in research and development in synthetic biology and microbiology.
• Experience in engineering bacterial strains for functions. This might include design, assembly, and modeling of genetic circuits
• Experience and knowledge in bacterial physiology such as bacterial sense and respond systems.
• Experience as an innovative experimentalist in genetic manipulations including experimental design, techniques, and execution.
• Ability to develop independent research projects as demonstrated through publication of peer-reviewed literature.
• Proficient verbal and written communication and interpersonal skills to collaborate effectively in a multidisciplinary team environment and present and explain technical information.
• Experience with high throughput screening methods such as FACS
• Experience with systems biology and multi-omics analyses, including genomics, transcriptomics, and proteomics and associated methods for data collection and analysis.
• Experience with gene editing in non-model strains (non-E. coli systems).
Pre-Employment Drug Test: External applicant(s) selected for this position will be required to pass a post-offer, pre-employment drug test. This includes testing for use of marijuana as Federal Law applies to us as a Federal Contractor.
Security Clearance: None required.
However, if your assignment is longer than 179 days cumulatively within a calendar year, you must go through the Personal Identity Verification process. This process includes completing an online background investigation form and receiving approval of the background check. (This process does not apply to foreign nationals.)
For additional information, please see DOE Order 472.2.
Note: This is a two year Postdoctoral appointment with the possibility of extension to a maximum of three years. Eligible candidates are those who have been awarded a PhD at time of hire date.
Lawrence Livermore National Laboratory (LLNL), located in the San Francisco Bay Area (East Bay), is a premier applied science laboratory that is part of the National Nuclear Security Administration (NNSA) within the Department of Energy (DOE). LLNL's mission is strengthening national security by developing and applying cutting-edge science, technology, and engineering that respond with vision, quality, integrity, and technical excellence to scientific issues of national importance. The Laboratory has a current annual budget of about $2.3 billion, employing approximately 6,900 employees.
LLNL is an affirmative action/ equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, marital status, national origin, ancestry, sex, sexual orientation, gender identity, disability, medical condition, protected veteran status, age, citizenship, or any other characteristic protected by law.